Article
Migraine association and linkage analyses of the human 5-hydroxytryptamine (5HT2A) receptor gene.
Cephalalgia : an international journal of headache - 1 Nov 1996
Nyholt D R, Curtain R P, Gaffney P T, Brimage P, Goadsby P J, Griffiths L R
Abstract excerpt
5-Hydroxytryptamine (5HT), commonly known as serotonin, which predominantly serves as an inhibitory neurotransmitter in the brain, has long been implicated in migraine pathophysiology. This study tested an MspI polymorphism in the human 5HT2A receptor gene (HTR2A) and a closely linked microsatellite marker (D13S126), for linkage and association with common migraine. In the association analyses, no significant...
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