Article
Family-based analysis of serotonin transporter gene polymorphisms in migraine with and without aura.
Cephalalgia : an international journal of headache - 1 Jul 2007
Karwautz A F K, Campos de Sousa S, Wöber C, Wagner G, Li T, Konrad A, Zesch H E, Zormann A, Berger G, Wanner C, Wöber-Bingöl C, Collier D A
Abstract excerpt
Genetic epidemiological twin studies have demonstrated a significant heritability for migraine, with > 60% of liability to migraine either with or without aura coming from additive genetic factors. Because of the essential role of serotonin in the pathophysiology and treatment of migraine, genes of the serotonin system are candidates for involvement in migraine. Consequently, we examined two functional VNTR...
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