Article
Novel alleles HLA-B*7802 and B*51022: evidence for convergency in the HLA-B5 family.
Tissue antigens - 1 Jan 1996
Prilliman K, Steiner N, Ellexson M, Stewart D, Lau M, Terasaki P, Hurley C, Hildebrand W
Abstract excerpt
We have characterized two novel HLA-B alleles, B*7802 and B*51022. The Caucasian-derived variant B*7802 most resembles the African-derived variant B*7801, from which B*7802 differs by two nucleotides. Only one of these modifications, however, is translated: a tyrosine for aspartate substitution occurs at residue 74 in B*7802, while the second nucleotide difference reflects a proximal synonymous substitution in...
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