Article
[Dose dependence of the frequency of micronucleated clone cells and division-related median clone size difference. II].
Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] - 1 Sept 1996
Hagemann G, Kreczik A, Treichel M
Abstract excerpt
PURPOSE: Following irradiation of the progenitor cells the clone growth of CHO cells decreases as a result of cell losses. Lethally acting expressions of micronuclei are produced by heritable lethal mutations. The dependency of the frequency of micronucleated binucleated clone cells and of the me...
Topics
- Animals
- CHO Cells
- Cell Count
- Cell Division
- Clone Cells
- Cricetinae
- Cricetulus
- Dose-Response Relationship, Radiation
- Genes, Lethal
- Micronuclei, Chromosome-Defective
- Models, Biological
- Mutation
- Radiation Dosage
- Rats
- Stem Cells
