Article
Low synonymous site variation at the lacY locus in Escherichia coli suggests the action of positive selection.
Journal of molecular evolution - 1 Feb 1996
Wagner R R, Riley M A
Abstract excerpt
We have determined the nucleotide sequences of seven lacY alleles isolated from natural isolates of Escherichia coli. Nucleotide heterozygosity estimates for this locus were compared to those obtained from previous studies of intraspecific variation at chromosomal loci, revealing that lacY has unusually low synonymous site variation. The average pairwise heterozygosity of synonymous sites (Ks = 0.0112 +/- 0.0100)...
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