Article
The impact of recombination on dN/dS within recently emerged bacterial clones.
PLoS pathogens - 1 Jul 2011
Castillo-Ramírez Santiago, Harris Simon R, Holden Matthew T G, He Miao, Parkhill Julian, Bentley Stephen D, Feil Edward J
Abstract excerpt
The development of next-generation sequencing platforms is set to reveal an unprecedented level of detail on short-term molecular evolutionary processes in bacteria. Here we re-analyse genome-wide single nucleotide polymorphism (SNP) datasets for recently emerged clones of methicillin resistant Staphylococcus aureus (MRSA) and Clostridium difficile. We note a highly significant enrichment of synonymous SNPs in...
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