Article
Modulation of beta2 integrin phenotype, adhesion, chemotaxis, and oxidative burst of neutrophils by cyclosporine.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie - 1 Feb 2001
Scavuzzo M, Sagripanti A, Mosca F, Ambrogi F
Abstract excerpt
Cyclosporine (CsA) is an immunosuppressive drug widely used to prevent allograft rejection, but its action on neutrophil function is not well known. Neutrophils play an important role in tissue damage during allograft rejection; chemotactic recruitment, adhesion to endothelial cells and oxidative burst of neutrophils are early events during allograft rejection. The aim of this work was to evaluate the effect of...
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