Article
The genetic basis of colorectal cancer risk.
Advances in internal medicine - 1 Jan 1996
Ahnen D J
Abstract excerpt
The genetic understanding of colon cancer susceptibility is advancing very rapidly; it has already had a major impact on clinical management, and we have only seen the beginning. Genes responsible for the two well-defined familial colon cancer syndromes (APC and HNPCC) have been identified. These syndromes can now often be diagnosed by genetic rather than by endoscopic screening of the at-risk individuals in a...
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