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Article

A nuclear role for the Fragile X mental retardation protein.

The EMBO journal - 1 Oct 1996

Fridell R A, Benson R E, Hua J, Bogerd H P, Cullen B R

Abstract excerpt

Fragile X syndrome results from lack of expression of a functional form of Fragile X mental retardation protein (FMRP), a cytoplasmic RNA-binding protein of uncertain function. Here, we report that FMRP contains a nuclear export signal (NES) that is similar to the NES recently identified in the R...

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Source

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Identifiers

PMID: 8895584
PMCID: PMC452283

Genes

NES
FMR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-8895584-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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A nuclear role for the Fragile X mental retardation protein.PMID 8895584Read ↗

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Mutational analysis establishes a critical role for the N terminus of fragile X mental retardation protein FMRP.Semantic proximity Read ↗

A missense variant in the nuclear export signal of the FMR1 gene causes intellectual disability.Semantic proximity Read ↗

Expression of fragile X mental retardation-1 gene with nuclear export signal mutation changes the expression profiling of mouse cerebella immortal neuronal cell.Semantic proximity Read ↗

An ‘’Omic’’ Overview of Fragile X SyndromeSemantic proximity Read ↗

FMRP ribonucleoprotein complexes and RNA homeostasis.Semantic proximity Read ↗

A novel fragile X syndrome mutation reveals a conserved role for the carboxy-terminus in FMRP localization and function.Semantic proximity Read ↗

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