Article
Loss of differences in mesangial cell phenotype between diabetic and normal rats: role of culture passages.
Biology of the cell - 1 Jan 1996
Ouardani M, Travo P, Bastie M J, Mornet D, Neff S, Leung-Tack J
Abstract excerpt
In mesangial cells (MC) isolated from streptozotocin (STZ)-induced diabetic rat kidneys, sensitivity to bradykinin (BK) for the induction of cell division and collagen synthesis, was found to be lower than in normal MC. Nevertheless, decreased activities could be reverted in vitro by insulin, at non-proliferative concentration (Girolami et al (1995), Can J Physiol Pharmacol 73, 848-853). The aim of the present...
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