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Article

Critical role of the virus-encoded microRNA-155 ortholog in the induction of Marek's disease lymphomas.

PLoS pathogens - 1 Feb 2011

Zhao Yuguang, Xu Hongtao, Yao Yongxiu, Smith Lorraine P, Kgosana Lydia, Green James, Petherbridge Lawrence, Baigent Susan J, Nair Venugopal

Abstract excerpt

Notwithstanding the well-characterised roles of a number of oncogenes in neoplastic transformation, microRNAs (miRNAs) are increasingly implicated in several human cancers. Discovery of miRNAs in several oncogenic herpesviruses such as KSHV has further highlighted the potential of virus-encoded miRNAs to contribute to their oncogenic capabilities. Nevertheless, despite the identification of several possible...

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Identifiers

PMID: 21383974
DOI: 10.1371/journal.ppat.1001305
PMCID: PMC3044692

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