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Article

Mutational analysis of RAG-1 in lymphoid malignancies.

Leukemia - 1 Nov 1996

Nomdedéu J, Lasa A, Seminago R, Mateu R, Rubiol E, Baiget M, Soler J

Abstract excerpt

Illegitimate recombinase activity promoted by the recombination activating RAG-1 and RAG-2 is assumed to be involved in the pathogenesis of the chromosomal translocations observed in lymphoid neoplasias. We analyzed the complete coding region of the RAG-1 gene in patients with lymphoid neoplasis using a multiple PCR-SSCP (single strand conformation polymorphism) strategy. Nine multiple myelomas, 17 non-Hodgkin's...

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PMID: 8892673

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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