Article
Recognition by human Vgamma9/Vdelta2 T cells of melanoma cells upon fusion with Daudi cells.
Immunogenetics - 1 Jan 1996
Viale O, van der Bruggen P, Meuer E, Kunzmann R, Kohler H, Mertelsmann R, Boon T, Fisch P
Abstract excerpt
Daudi Burkitt's lymphoma cells, unlike other tumor cell lines, stimulate human T cells coexpressing the variable (V) region genes TCRG-V9 and V TCRD-V2 to proliferate and secrete lymphokines. Hybrids, derived by the fusion of Daudi cells with the human melanoma cell line MZ2-MEL 2.2, retain the morphology of melanoma cells. Unlike the parental melanoma cell line, these Daudi x MZ2-MEL 2.2 hybrids stimulate...
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