Article
Refined structures of bobwhite quail lysozyme uncomplexed and complexed with the HyHEL-5 Fab fragment.
Proteins - 1 Sept 1996
Chacko S, Silverton E W, Smith-Gill S J, Davies D R, Shick K A, Xavier K A, Willson R C, Jeffrey P D, Chang C Y, Sieker L C, Sheriff S
Abstract excerpt
The HyHEL-5 antibody has more than a thousandfold lower affinity for bobwhite quail lysozyme (BWQL) than for hen egg-white lysozyme (HEL). Four sequence differences exist between BWQL and HEL, of which only one is involved in the interface with the Fab. The structure of bobwhite quail lysozyme ha...
Topics
- Animals
- Antigen-Antibody Complex
- Chickens
- Crystallization
- Crystallography, X-Ray
- Egg Proteins
- Epitope Mapping
- Hydrogen Bonding
- Immunoglobulin Fab Fragments
- Models, Molecular
- Muramidase
- Mutation
- Protein Conformation
- Quail
- Water