Article
Enhanced cell permeability increases the sensitivity of a yeast test for mutagens.
Mutation research - 13 Sept 1996
Staleva L, Waltscheva L, Golovinsky E, Venkov P
Abstract excerpt
ts1 is a mutation which causes a general increase in permeability of Sacharomyces cerevisiae cells in an unspecific manner. The introduction of the ts1 mutation under homozygous conditions into the D7 diploid strain enhanced the sensitivity of the test system described by Zimmermann et al. (1975). The newly constructed strain D7ts1 responded with a four to six times higher frequency compared to the D7 strain for...
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