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Article

A mutation in HERG associated with notched T waves in long QT syndrome.

Journal of molecular and cellular cardiology - 1 Aug 1996

Dausse E, Berthet M, Denjoy I, André-Fouet X, Cruaud C, Bennaceur M, Fauré S, Coumel P, Schwartz K, Guicheney P

Abstract excerpt

Long QT syndrome (LQT) is a genetically heterogeneous inherited disorder that causes sudden death from cardiac arrhythmia. Four loci have been mapped to chromosomes 3, 4, 7 and 11 and three specific mutated genes for LQT syndrome have been identified. LQT2 results from mutations in the human ether-a-gogo-related gene, HERG, a cardiac potassium channel, whose protein product likely underlies Ikd the rapidly...

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Identifiers

PMID: 8877771
DOI: 10.1006/jmcc.1996.0151

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

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Click a neighbor to travelStep 1 · 12 closest

A mutation in HERG associated with notched T waves in long QT syndrome.PMID 8877771Read ↗

Missense mutation in the pore region of HERG causes familial long QT syndrome.Semantic proximity Read ↗

A missense mutation (G604S) in the S5/pore region of HERG causes long QT syndrome in a Chinese family with a high incidence of sudden unexpected death.Semantic proximity Read ↗

A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndromeSemantic proximity Read ↗

Long QT syndrome: cellular basis and arrhythmia mechanism in LQT2.Semantic proximity Read ↗

Romano-Ward long QT syndrome: identification of a HERG mutation in a Taiwanese kindred.Semantic proximity Read ↗

Long QT syndrome with a high mortality rate caused by a novel G572R missense mutation in KCNH2.Semantic proximity Read ↗

Aborted Cardiac Arrest in LQT2 Related to Novel KCNH2 (hERG) Variant Identified in One Lithuanian Family.Semantic proximity Read ↗

Survey of the coding region of the HERG gene in long QT syndrome reveals six novel mutations and an amino acid polymorphism with possible phenotypic effects.Semantic proximity Read ↗

A K+ Channel Splice Variant Common in Human Heart Lacks a C-terminal Domain Required for Expression of Rapidly Activating Delayed Rectifier CurrentSemantic proximity Read ↗

The long QT syndrome: a novel missense mutation in the S6 region of the KVLQT1 gene.Semantic proximity Read ↗

Human ether-a-go-go related gene (hERG) K+ channels: function and dysfunction.Semantic proximity Read ↗

HERG, a human inward rectifier in the voltage-gated potassium channel family.Semantic proximity Read ↗

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