Article
Similarity of in vivo somatic mutations at an autosomal adenine phosphoribosyltransferase locus between T- and B-cells in human peripheral blood.
Mutation research - 25 Oct 1996
Hakoda M, Kamatani N, Terai C, Yamanaka H, Taniguchi A, Ueda H, Kashiwazaki S
Abstract excerpt
In vivo somatic mutations have been detected at several human loci by using clonal cultures of peripheral blood T-cells. It has not been fully understood whether or not the somatic mutations in T-cells are similar to those of other cell types. To address this issue, we cloned, from human peripheral blood, T- and B-cells with mutations at an autosomal adenine phosphoribosyltransferase (APRT) locus. For the...
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