Article
BRCA1-related papillary serous carcinoma of the peritoneum has a unique molecular pathogenesis.
Cancer research - 1 Mar 2000
Schorge J O, Muto M G, Lee S J, Huang L W, Welch W R, Bell D A, Keung E Z, Berkowitz R S, Mok S C
Abstract excerpt
Papillary serous carcinoma of the peritoneum (PSCP) is believed to develop de novo from the peritoneal lining of the pelvis and abdomen. Although it is histologically indistinguishable from serous ovarian carcinoma, PSCP exhibits minimal or absent ovarian involvement and may even develop in a woman years after prophylactic oophorectomy. We have shown previously that patients with germ-line BRCA1 mutations who...
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