Mapping the adhesive domains of the myelin Po protein.

doi:10.1002/(SICI)1097-4547(19960901)45:5<525::AID-JNR2>3.0.CO;2-E

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Article

Mapping the adhesive domains of the myelin Po protein.

Journal of neuroscience research - 1 Sept 1996

Zhang K, Merazga Y, Filbin M T

Abstract excerpt

The Po protein holds PNS myelin compact at the intraperiod line by homophilic interactions of its single immunoglobulin (Ig)-like domain. Using transfected Chinese hamster ovary (CHO) cells expressing Po we can monitor this adhesion in vitro and have shown that the cells expressing Po when incuba...

Topics

Adhesiveness
Amino Acid Sequence
Animals
Blotting, Western
CHO Cells
Cell Adhesion
Conserved Sequence
Cricetinae
Fluorescent Antibody Technique, Indirect
Gene Amplification
Membrane Proteins
Molecular Sequence Data
Mutation
Myelin P0 Protein
Peptide Mapping
Peripheral Nervous System
Transfection

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