Article
Mapping the adhesive domains of the myelin Po protein.
Journal of neuroscience research - 1 Sept 1996
Zhang K, Merazga Y, Filbin M T
Abstract excerpt
The Po protein holds PNS myelin compact at the intraperiod line by homophilic interactions of its single immunoglobulin (Ig)-like domain. Using transfected Chinese hamster ovary (CHO) cells expressing Po we can monitor this adhesion in vitro and have shown that the cells expressing Po when incubated as a single-cell suspension form large aggregates, whereas control-transfected cells do not. To precisely map the...
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