Article
Lysophospholipase L2 of Vibrio cholerae O1 affects cholera toxin production.
FEMS immunology and medical microbiology - 1 Aug 1996
Whayeb S A, Yamamoto K, Castillo M E, Tojo H, Honda T
Abstract excerpt
The implication in cholera toxin (CT) production of the newly identified gene, lypA, that encodes the lysophospholipase L2 of Vibrio cholerae, was investigated. Introduction of lypA into the V. cholerae O1 mutant (NF404), which has a Tn5-insertion in lypA and has lost CT as well as haemolysin production, restored the lysophospholipase activity and CT production but not the haemolytic activity. Inactivation of the...
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