Article
High nucleotide sequence variation in a region of low recombination in Drosophila simulans is consistent with the background selection model.
Molecular biology and evolution - 1 Oct 1996
Hamblin M T, Aquadro C F
Abstract excerpt
We surveyed nucleotide sequence variation at glucose dehydrogenase (Gld), in a region of low recombination on chromosome 3R, from a population sample of Drosophila simulans. The levels of nucleotide variation were surprisingly high. There was no departure from the expectation of a neutral model for the level of polymorphism, indicating no evidence of a selective sweep in this region. There was a significant...
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