Article
Mutations in GCR3, a gene involved in the expression of glycolytic genes in Saccharomyces cerevisiae, suppress the temperature-sensitive growth of hpr1 mutants.
Genetics - 1 Apr 1996
Uemura H, Pandit S, Jigami Y, Sternglanz R
Abstract excerpt
To study the functions of DNA topoisomerase I and Hpr1 protein, a suppressor mutant of the temperature-sensitive growth of an hpr1 top1-5ts double mutant was isolated. The isolated triple mutant showed cold-sensitive growth. By complementation of this phenotype, the suppressor gene was cloned. DN...
Topics
- Alleles
- Amino Acid Sequence
- DNA Topoisomerases, Type I
- Fungal Proteins
- Gene Expression Regulation, Fungal
- Glycolysis
- Introns
- Molecular Sequence Data
- Nuclear Proteins
- Plasmids
- RNA Cap-Binding Proteins
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Suppression, Genetic
- Temperature