Identification of regB, a gene required for optimal exotoxin A yields in Pseudomonas aeruginosa.

doi:10.1111/j.1365-2958.1990.tb00615.x

Back to search

Article

Identification of regB, a gene required for optimal exotoxin A yields in Pseudomonas aeruginosa.

Molecular microbiology - 1 Mar 1990

Wick M J, Frank D W, Storey D G, Iglewski B H

Abstract excerpt

The yield of exotoxin A from Pseudomonas aeruginosa has been shown to be strain-dependent. Exotoxin A production requires the presence of the positive regulatory gene, regA. We cloned the regA genetic locus from the prototypical P. aeruginosa strain PAO1 and examined its ability to influence exot...

Topics

ADP Ribose Transferases
Amino Acid Sequence
Bacterial Toxins
Base Sequence
Cloning, Molecular
DNA, Bacterial
Exotoxins
Genes, Regulator
Molecular Sequence Data
Mutation
Pseudomonas aeruginosa
Virulence Factors
Pseudomonas aeruginosa Exotoxin A

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.