Article
Ferric uptake regulator mutants of Pseudomonas aeruginosa with distinct alterations in the iron-dependent repression of exotoxin A and siderophores in aerobic and microaerobic environments.
Molecular microbiology - 1 Sept 1996
Barton H A, Johnson Z, Cox C D, Vasil A I, Vasil M L
Abstract excerpt
Because the ferric uptake regulator (fur) appears to be an essential gene in Pseudomonas aeruginosa, resistance to manganese was used as an enrichment to isolate strains carrying point mutations in the fur gene in order to assess its role in the co-ordinate expression of siderophores and exotoxin...
Topics
- ADP Ribose Transferases
- Bacterial Proteins
- Bacterial Toxins
- Biological Transport
- DNA Footprinting
- DNA-Binding Proteins
- Exotoxins
- Gene Expression Regulation, Bacterial
- Iron
- Molecular Sequence Data
- Mutation
- Promoter Regions, Genetic
- Protein Binding
- Pseudomonas aeruginosa