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Article

The Mus musculus domesticus Tdy allele acts later than the Mus musculus musculus Tdy allele: a basis for XY sex-reversal in C57BL/6-YPOS mice.

Development (Cambridge, England) - 1 Oct 1991

Palmer S J, Burgoyne P S

Abstract excerpt

Consomic C57BL/6 males, carrying either the Mus musculus musculus-derived C57BL/6 Y chromosome or the Mus musculus domesticus-derived Poschiavinus Y chromosome, were outcrossed to females of the inbred strains C3H/Bi and CXBH/By and to females of the random bred strain MF1/Ola. In a study at 12.5 days post coitum, gonads of XYC57 and XYPOS fetuses were assessed for the presence of testicular cords. It was found...

Topics

Alleles
Animals
Disorders of Sex Development
Female
Gene Expression
Gestational Age
Male
Mice
Ovary
Phenotype
Sex Differentiation
Testis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 1782876
DOI: 10.1242/dev.113.2.709

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1782876-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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The Mus musculus domesticus Tdy allele acts later than the Mus musculus musculus Tdy allele: a basis for XY sex-reversal in C57BL/6-YPOS mice.PMID 1782876Read ↗

Sex-determining genes on mouse autosomes identified by linkage analysis of C57BL/6J-YPOS sex reversal.Semantic proximity Read ↗

Ontogenic and morphological study of gonadal formation in genetically-modified sex reversal XY(POS) mice.Semantic proximity Read ↗

The testis-determining autosomal trait, Tda-1, of C57BL/6J is determined by more than a single autosomal gene when compared with DBA/2J mice.Semantic proximity Read ↗

The chromosome 11 region from strain 129 provides protection from sex reversal in XYPOS mice.Semantic proximity Read ↗

A single genetic determinant that prevents sex reversal in C57BL-YPOS congenic mice.Semantic proximity Read ↗

Does one gene determine whether a C57BL/6J-Y(POS) mouse will develop as a female or as an hermaphrodite?Semantic proximity Read ↗

XY female mice resulting from a heritable mutation in the primary testis-determining gene, Tdy.Semantic proximity Read ↗

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Sex-reversed mice: XX and XO malesSemantic proximity Read ↗

C57BL/6J-T-associated sex reversal in mice is caused by reduced expression of a Mus domesticus Sry allele.Semantic proximity Read ↗

Tdy-negative XY, XXY and XYY female mice: breeding data and synaptonemal complex analysis.Semantic proximity Read ↗

Segregation analysis of the testis-determining autosomal trait, Tda, that differs between the C57Bl/6J and DBA/2J mouse strains suggests a multigenic threshold model.Semantic proximity Read ↗

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