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Article

Familial tumor syndrome associated with a germline nonfunctional p16INK4a allele.

Journal of the National Cancer Institute - 16 Oct 1996

Yarbrough W G, Aprelikova O, Pei H, Olshan A F, Liu E T

Abstract excerpt

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Share to Carcinoma, Squamous Cell
Share to Cyclin-Dependent Kinase Inhibitor p16
Share to DNA, Neoplasm
Share to Genes, Tumor Suppressor

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Germ-Line Mutation

Share to Head and Neck Neoplasms

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Source

Identifiers

PMID: 8841025
DOI: 10.1093/jnci/88.20.1489

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Familial tumor syndrome associated with a germline nonfunctional p16INK4a allele.PMID 8841025Read ↗

Noncoding germline mutations in p16/CDKN2A in melanoma-prone families.Semantic proximity Read ↗

Identification of a splice acceptor site mutation in p16INK4A/p14ARF within a breast cancer, melanoma, neurofibroma prone kindred.Semantic proximity Read ↗

p16INK4A as a human tumor suppressor.Semantic proximity Read ↗

Germline p16INK4A mutation and protein dysfunction in a family with inherited melanoma.Semantic proximity Read ↗

Functional, structural, and genetic evaluation of 20<i>CDKN2A</i>germ line mutations identified in melanoma-prone families or patientsSemantic proximity Read ↗

CDKN2A (p16INK4A) somatic and germline mutations.Semantic proximity Read ↗

Germline p16 mutations in familial melanomaSemantic proximity Read ↗

Analysis of the p16 gene status of non-familial dysplastic nevus syndrome patients.Semantic proximity Read ↗

Functional evaluation of tumour-specific variants of p16INK4a/CDKN2A: correlation with protein structure information.Semantic proximity Read ↗

Germline mutations in the p16INK4a binding domain of CDK4 in familial melanomaSemantic proximity Read ↗

Aberrant expression of p16INK4a in human cancers – a new biomarker?Semantic proximity Read ↗

A frequent polymorphism in exon 1 of the p16/CDKN2 gene.Semantic proximity Read ↗

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