Article
Are there alternative avian influenza viruses for generation of stable attenuated avian-human influenza A reassortant viruses?
Virus research - 1 Dec 1995
Subbarao K, Webster R G, Kawaoka Y, Murphy B R
Abstract excerpt
The present study evaluated gull influenza A viruses as donors of attenuating genes for the production of live, attenuated influenza A H1N1 and H3N2 avian-human (ah) reassortant viruses for use as vaccines to prevent disease due to influenza A viruses in humans. The previously evaluated duck influenza A viruses were abandoned as donors of attenuating avian influenza virus genes because clinical evaluation of H1N1...
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