Phenotypic differences between oral and skin fibroblasts in wound contraction and growth factor expression.

doi:10.1111/j.1743-6109.2006.00107.x

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Phenotypic differences between oral and skin fibroblasts in wound contraction and growth factor expression.

Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society - 1 Jan 2000

Shannon Diane B, McKeown Scott T W, Lundy Fionnuala T, Irwin Chris R

Abstract excerpt

Wounds of the oral mucosa heal in an accelerated fashion with reduced scarring compared with cutaneous wounds. The differences in healing outcome between oral mucosa and skin could be because of phenotypic differences between the respective fibroblast populations. This study compared paired mucosal and dermal fibroblasts in terms of collagen gel contraction, alpha-smooth muscle actin expression (alpha-SMA), and...

Topics

Actins
Adult
Analysis of Variance
Animals
Blotting, Western
Cells, Cultured
Collagen
Enzyme-Linked Immunosorbent Assay
Female
Fibroblasts
Gels

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Growth Substances

Humans

Mouth Mucosa

Phenotype

Rats

Statistics, Nonparametric

Wound Healing

Source

Open in PubMed

Identifiers

PMID: 16630106
DOI: 10.1111/j.1743-6109.2006.00107.x

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phenotypic differences between oral and skin fibroblasts in wound contraction and growth factor expression.PMID 16630106Read ↗

Human Gingival Fibroblasts Display a Non-Fibrotic Phenotype Distinct from Skin Fibroblasts in Three-Dimensional CulturesSemantic proximity Read ↗

Phenotypic variation in the production of bioactive hepatocyte growth factor/scatter factor by oral mucosal and skin fibroblasts.Semantic proximity Read ↗

The diverse role of oral fibroblasts in normal and diseaseSemantic proximity Read ↗

FGF and TGF-β growth factor isoform modulation of human gingival and periodontal ligament fibroblast wound healing phenotype.Semantic proximity Read ↗

A comparison of the ability of intra-oral and extra-oral fibroblasts to stimulate extracellular matrix reorganization in a model of wound contraction.Semantic proximity Read ↗

Fibroblasts from the oral masticatory and lining mucosa have different gene expression profiles and proliferation ratesSemantic proximity Read ↗

Phenotypic markers of oral keratinocytes seeded on two distinct 3D oral mucosa models.Semantic proximity Read ↗

Hyaluronan Facilitates Transforming Growth Factor-β1-mediated Fibroblast ProliferationSemantic proximity Read ↗

Recombinant Humanized Collagen Type I Promotes Oral Ulcer Healing via HGF/TGF-β3-Mediated Fibroblast ActivationSemantic proximity Read ↗

Distinct phenotype and therapeutic potential of gingival fibroblasts.Semantic proximity Read ↗

<i>In vitro</i> effects of tensile strain on cancer-associated and matched normal fibroblasts derived from oral squamous cell carcinoma: an exploratory studySemantic proximity Read ↗

Exosomal miR-17-5p derived from epithelial cells is involved in aberrant epithelium-fibroblast crosstalk and induces the development of oral submucosal fibrosisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.