Article
Phenotypic markers of oral keratinocytes seeded on two distinct 3D oral mucosa models.
Toxicology in vitro : an international journal published in association with BIBRA - 1 Sept 2018
Basso Fernanda G, Pansani Taisa N, Marcelo Cyntia L, de Souza Costa Carlos Alberto, Hebling Josimeri, Feinberg Stephen E
Abstract excerpt
This study validates the use of a full-thickness oral mucosa model for in vitro studies with a collagen type I matrix, by comparison of this model with two other 3D oral mucosa models: human-sourced and porcine acellular dermal matrices (AlloDerm®/Strattice®, respectively). For the collagen matrix model, gingival fibroblasts were seeded either onto the dermal side of the AlloDerm® and Strattice® matrices or...
Topics
- Animals
- Cell Culture Techniques
- Cell Proliferation
- Collagen
- Collagen Type I
- Collagen Type I, alpha 1 Chain
- Epidermal Growth Factor
- Fibroblast Growth Factor 7
- Fibroblasts
- Gene Expression
- Gingiva
- Glucose
- Humans
- Keratinocytes