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In leukaemic CD5+ B cells the expression of BCL‐2 gene family is shifted toward protection from apoptosis

1 Sept 1996

Abstract excerpt

This study further investigated the mechanisms that control apoptosis in leukaemic CD5+ B cells, and focused on the Bcl-2 gene family. The pattern of expression of Bcl-2, Bcl-xL, Bcl-xS and Bax genes, selected because of their interrelated role in the control of apoptosis, was analysed in a series of CD5+ B-cell chronic lymphoid leukaemias. Cells from 34 patients with chronic lymphoid leukaemia of B-cell type (23...

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PMID: 8826882
DOI: 10.1046/j.1365-2141.1996.d01-1856.x

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