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Article

Aberrant human tissue kallikrein levels in the stratum corneum and serum of patients with psoriasis: dependence on phenotype, severity and therapy.

The British journal of dermatology - 1 May 2007

Komatsu N, Saijoh K, Kuk C, Shirasaki F, Takehara K, Diamandis E P

Abstract excerpt

BACKGROUND: Human tissue kallikreins (KLKs) are a family of 15 trypsin-like or chymotrypsin-like secreted serine proteases (KLK1-KLK15). Multiple KLKs have been quantitatively identified in normal stratum corneum (SC) and sweat as candidate desquamation-related proteases. OBJECTIVES: To quantify KLK5, KLK6, KLK7, KLK8, KLK10, KLK11, KLK13 and KLK14 in the SC and serum of patients with psoriasis, and their...

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Source

Identifiers

PMID: 17459012
DOI: 10.1111/j.1365-2133.2006.07743.x

Genes

KLK10
KLK13
KLK6
KLK11
KLK5
KLK7
KLK8
KLK1
KLK14
KLK15

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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