Meningococcal Opa and Opc proteins: their role in colonization and invasion of human epithelial and endothelial cells.

doi:10.1111/j.1365-2958.1993.tb00922.x

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Article

Meningococcal Opa and Opc proteins: their role in colonization and invasion of human epithelial and endothelial cells.

Molecular microbiology - 1 Nov 1993

Virji M, Makepeace K, Ferguson D J, Achtman M, Moxon E R

Abstract excerpt

Neisseria meningitidis (Nm) isolates from disease or during carriage express, on their outer membranes, one or more of a family of closely related proteins designated Opa proteins. In this study, we have examined the potential roles of Nm Opa proteins in bacterial attachment and invasion of endothelial as well as epithelial cells and compared the influence of Opa proteins with that of Opc protein, which has been...

Topics

Animals
Antibodies, Bacterial
Bacterial Adhesion
Bacterial Outer Membrane Proteins
Cattle
Cells, Cultured
Endothelium, Vascular
Epithelial Cells
Epithelium
Humans
Lipopolysaccharides

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Microscopy, Electron

N-Acetylneuraminic Acid

Neisseria meningitidis

Phenotype

Sialic Acids

Tumor Cells, Cultured

Virulence

Source

Open in PubMed

Identifiers

PMID: 7968528
DOI: 10.1111/j.1365-2958.1993.tb00922.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7968528-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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