Article
Mutations in masquerade, a novel serine-protease-like molecule, affect axonal guidance and taste behavior in Drosophila.
Mechanisms of development - 1 Jun 1996
Murugasu-Oei B, Balakrishnan R, Yang X, Chia W, Rodrigues V
Abstract excerpt
The masquerade (mas) locus encodes an extracellular molecule with a striking similarity to serine proteases. The serine residue, which is essential for enzymatic activity, has been substituted by glycine, suggesting that MAS could serve to antagonize serine protease activity [Murugasu-Oei et al....
Topics
- Animals
- Axons
- Drosophila
- Drosophila Proteins
- Embryo, Nonmammalian
- In Situ Hybridization
- Insect Proteins
- Larva
- Mutation
- Nervous System
- Pupa
- RNA, Messenger
- Serine Endopeptidases
- Serine Proteinase Inhibitors
- Taste