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Article

The proprotein convertase amontillado (amon) is required during Drosophila pupal development.

Developmental biology - 1 Sept 2009

Rayburn Lowell Y M, Rhea Jeanne, Jocoy Steven R, Bender Michael

Abstract excerpt

Peptide hormones governing many developmental processes are generated via endoproteolysis of inactive precursor molecules by a family of subtilisin-like proprotein convertases (SPCs). We previously identified mutations in the Drosophila amontillado (amon) gene, a homolog of the vertebrate neuroendocrine-specific Prohormone Convertase 2 (PC2) gene, and showed that amon is required during embryogenesis, early...

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Identifiers

PMID: 19559693
DOI: 10.1016/j.ydbio.2009.06.021
PMCID: PMC2753176

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