Article
The cytoplasmic adaptor protein Caskin mediates Lar signal transduction during Drosophila motor axon guidance.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 23 Mar 2011
Weng Yi-Lan, Liu Nan, DiAntonio Aaron, Broihier Heather T
Abstract excerpt
The multiprotein complexes that receive and transmit axon pathfinding cues during development are essential to circuit generation. Here, we identify and characterize the Drosophila sterile α-motif (SAM) domain-containing protein Caskin, which shares homology with vertebrate Caskin, a CASK [calcium/calmodulin-(CaM)-activated serine-threonine kinase]-interacting protein. Drosophila caskin (ckn) is necessary for...
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