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Article

[A sensitive fluorescent assay for the detection and quantification of mitochondrial 3243 mutation].

Rinsho byori. The Japanese journal of clinical pathology - 1 Aug 1996

Yu G S, Otabe S, Niwa M

Abstract excerpt

A mutation at nucleotide 3243 in the mitochondrial DNA (mtDNA) specifying tRNALeu(UUR) has been shown to be related with diabetes mellitus. Since mtDNA shows heteroplasmy and its composition would change among various tissues, it is important to quantitate the percentage of mutant mtDNA precisely. Here we report a rapid and sensitive method to determine the mutant mtDNA. A fragment of mtDNA containing nucleotide...

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Identifiers

PMID: 8816065

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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