Article
A fluorescent multiplex ARMS method for rapid mutation analysis.
Molecular and cellular probes - 1 Dec 1995
Zschocke J, Graham C A
Abstract excerpt
The amplification refractory mutation system (ARMS) is a powerful technique for the identification of mutations. We present a modification of this technique involving coamplification of normal and mutant alleles with primers that differ in length by three to five bases. Fluorescent labelling allows exact sizing of the amplification products on an automated DNA fragment analyser. We have used the fluorescent...
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