Development, multiplexing, and application of ARMS tests for common mutations in the CFTR gene.

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Article

Development, multiplexing, and application of ARMS tests for common mutations in the CFTR gene.

American journal of human genetics - 1 Aug 1992

Ferrie R M, Schwarz M J, Robertson N H, Vaudin S, Super M, Malone G, Little S

Abstract excerpt

The amplification refractory mutation system (ARMS) is a simple, rapid and reliable method for the detection of any mutation involving single base changes or small deletions. We have applied ARMS methodology to the detection of mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. Single ARMS tests have been developed for 11 CFTR mutations found in the northwest of England. ARMS...

Topics

Base Sequence
Cystic Fibrosis
Cystic Fibrosis Transmembrane Conductance Regulator
DNA
DNA, Single-Stranded
England
Evaluation Studies as Topic
Genotype
Heterozygote
Homozygote
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Membrane Proteins

Molecular Sequence Data

Mutation

Nucleic Acid Amplification Techniques

Predictive Value of Tests

Terminology as Topic

Source

Open in PubMed Open full text

Identifiers

PMID: 1379414
PMCID: PMC1682690

Genes

CFTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1379414-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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