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Development and validation of a cost-effective in-house method, tetra-primer ARMS PCR assay, in genotyping of seven clinically important point mutations.

Molecular and cellular probes - 1 Aug 2011

Etlik Ozdal, Koksal Vedat, Arican-Baris S Tugba, Baris Ibrahim

Abstract excerpt

The single nucleotide polymorphism (SNP) genotyping is currently considered as a particularly valuable tool for the diagnosis of different pathologies. For this reason, over the past several years a great deal of effort has been devoted to developing accurate, rapid, and cost-effective technologies for SNP analysis. Although a large number of distinct approaches has been reported each laboratory use one of the...

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DNA Primers
Genotype
Point Mutation
Polymerase Chain Reaction
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Reproducibility of Results

Sensitivity and Specificity

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PMID: 21530640
DOI: 10.1016/j.mcp.2011.04.005

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