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Article

Pharmacokinetics and absolute bioavailability of lansoprazole.

European journal of clinical pharmacology - 1 Jan 1996

Gerloff J, Mignot A, Barth H, Heintze K

Abstract excerpt

OBJECTIVE: In a crossover study 12 healthy volunteers received lansoprazole 15 mg or 30 mg orally, or 15 mg intravenously in randomized order as a single dose. Blood samples were taken and plasma levels of lansoprazole were determined using an HPLC method. The volunteers were phenotyped for the debrisoquine/sparteine and mephenytoin polymorphisms. RESULTS: The total clearance was 517 ml.min-1, and the absolute...

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Identifiers

PMID: 8803522
DOI: 10.1007/s002280050111

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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