Article
Comparison of the pharmacokinetics of moclobemide in poor and efficient metabolizers of debrisoquine.
Acta psychiatrica Scandinavica. Supplementum - 1 Jan 1990
Schoerlin M P, Blouin R A, Pfefen J P, Guentert T W
Abstract excerpt
A number of pharmacokinetics studies in which patients had been phenotyped and poor metabolizers for moclobemide found were analysed retrospectively. There were 27 subjects in all, aged between 19 and 75 years, and 5 of these were classified as poor debrisoquine metabolizers. Although there was a wide variability in the pharmacokinetic parameters observed, no consistent relationship was found between these and...
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