Comparison of the pharmacokinetics of moclobemide in poor and efficient metabolizers of debrisoquine.

doi:10.1111/j.1600-0447.1990.tb05347.x

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Article

Comparison of the pharmacokinetics of moclobemide in poor and efficient metabolizers of debrisoquine.

Acta psychiatrica Scandinavica. Supplementum - 1 Jan 1990

Schoerlin M P, Blouin R A, Pfefen J P, Guentert T W

Abstract excerpt

A number of pharmacokinetics studies in which patients had been phenotyped and poor metabolizers for moclobemide found were analysed retrospectively. There were 27 subjects in all, aged between 19 and 75 years, and 5 of these were classified as poor debrisoquine metabolizers. Although there was a...

Topics

Adult
Aged
Antidepressive Agents
Benzamides
Biological Availability
Debrisoquin
Female
Half-Life
Humans
Male
Metabolic Clearance Rate
Middle Aged
Moclobemide
Monoamine Oxidase Inhibitors
Phenotype

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