Article
Pharmacokinetics of pantoprazole in man.
International journal of clinical pharmacology and therapeutics - 1 May 1996
Huber R, Hartmann M, Bliesath H, Lühmann R, Steinijans V W, Zech K
Abstract excerpt
The proton pump inhibitor pantoprazole is a substituted benzimidazole sulphoxide for the treatment of acid-related gastrointestinal diseases such as reflux esophagitis, duodenal and gastric ulcers. Pantoprazole, administered as a 40 mg enteric coated tablet, is quantitatively absorbed. Its absolute bioavailability is 77% and does not change upon multiple dosing. Following a single oral dose of 40 mg, Cmax is...
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