Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification and characterization of two alternative splice variants of human interleukin-2.

The Journal of biological chemistry - 20 Sept 1996

Tsytsikov V N, Yurovsky V V, Atamas S P, Alms W J, White B

Abstract excerpt

Our previous work showed that alternative splicing is used to make an inhibitory variant of human interleukin (IL)-4. Because of homology between IL-4 and IL-2 proteins and receptors, we tested whether alternative splicing is used to generate similar inhibitory variants of human IL-2. Messenger RNA from peripheral blood mononuclear cells was subjected to reverse transcription-polymerase chain reaction using IL-2...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alternative Splicing
Share to Dose-Response Relationship, Drug

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Variation

Share to Lymphocyte Activation

Share to Polymerase Chain Reaction

Share to RNA, Messenger

Share to Sequence Analysis, DNA

Share to T-Lymphocytes

Source

Identifiers

PMID: 8798495
DOI: 10.1074/jbc.271.38.23055

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification and characterization of two alternative splice variants of human interleukin-2.PMID 8798495Read ↗

An alternative splice variant of human IL-4, IL-4 δ 2, inhibits IL-4-stimulated T cell proliferationSemantic proximity Read ↗

Interleukin and interleukin receptor diversity: role of alternative splicing.Semantic proximity Read ↗

The Murine Irak2 Gene Encodes Four Alternatively Spliced Isoforms, Two of Which Are InhibitorySemantic proximity Read ↗

Cloning and identification of two novel splice variants of human PD-L2.Semantic proximity Read ↗

Cloning and Characterization of an Alternatively Processed Human Type II Interleukin-1 Receptor mRNASemantic proximity Read ↗

Length variation within intron 2 of the human IL-1 receptor antagonist protein gene (IL1RN).Semantic proximity Read ↗

Novel interleukin-2 dependent T-cell line derived from adult T-cell leukemia not associated with human T-cell leukemia virus type I.Semantic proximity Read ↗

Soluble interleukin‐6 receptors released from T cell or granulocyte/macrophage cell lines and human peripheral blood mononuclear cells are generated through an alternative splicing mechanismSemantic proximity Read ↗

Identification of beta1C-2, a novel variant of the integrin beta1 subunit generated by utilization of an alternative splice acceptor site in exon C.Semantic proximity Read ↗

Natural Splicing of Exon 2 of Human Interleukin-15 Receptor α-Chain mRNA Results in a Shortened Form with a Distinct Pattern of ExpressionSemantic proximity Read ↗

Novel interleukin-1 receptor antagonist exon polymorphisms and their use in allele-specific mRNA assessment.Semantic proximity Read ↗

Expression and purification of a mutant of human interleukin-2 in Pichia pastoris.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.