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Article

<scp>PMEL</scp>: a pigment cell‐specific model for functional amyloid formation

25 Jan 2013

Abstract excerpt

PMEL is a pigment cell-specific protein responsible for the formation of fibrillar sheets within the pigment organelle, the melanosome. The fibrillar sheets serve as a template upon which melanins polymerize as they are synthesized. The PMEL fibrils are required for optimal pigment cell function, as animals that either lack PMEL expression or express mutant PMEL variants show varying degrees of hypopigmentation...

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PMID: 23350640
DOI: 10.1111/pcmr.12067

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<scp>PMEL</scp>: a pigment cell‐specific model for functional amyloid formationPMID 23350640Read ↗

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