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Article

Evaluation of new approaches to poliovirus vaccine neurovirulence tests.

Developments in biological standardization - 1 Jan 1996

Wood D J

Abstract excerpt

Transgenic mice that express the human receptor for poliovirus and mutant analysis by PCR followed by restriction enzyme cleavage (MAPREC) are two new approaches to poliovirus vaccine neurovirulence testing. This review assesses the validity and current status of these tests. Both approaches require further rigorous validation and development. They are most likely to be used as corollary rather than replacement...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 8785995

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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