Article
An antimicrobial peptide, magainin 2, induced rapid flip-flop of phospholipids coupled with pore formation and peptide translocation.
Biochemistry - 3 Sept 1996
Matsuzaki K, Murase O, Fujii N, Miyajima K
Abstract excerpt
The effect of an antimicrobial peptide, magainin 2, on the flip-flop rates of phospholipids was investigated by use of fluorescent lipids, i.e., anionic N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)dipalmitoyl-L-alpha- phosphatidylethanolamine (NBD-PE), 1-oleoyl-2-[12-((7-nitrobenz-2-oxa-1,3-diazol-4-yl)...
Topics
- Amino Acid Sequence
- Animals
- Anti-Infective Agents
- Antimicrobial Cationic Peptides
- Diffusion
- Dithionite
- Fluoresceins
- Fluorescent Dyes
- Kinetics
- Lipid Bilayers
- Liposomes
- Magainins
- Mathematics
- Molecular Sequence Data
- Mutation
- Peptides
- Permeability
- Phosphatidylethanolamines