Article
The role of individual susceptibility in cancer burden related to environmental exposure.
Environmental health perspectives - 1 May 1996
Bartsch H, Hietanen E
Abstract excerpt
Individual susceptibility to cancer may result from host factors including differences n metabolism, DNA repair, altered expression of protooncogenes and tumor suppressor genes, and nutritional status. Since most carcinogens require metabolic activation before binding to DNA, variations in an individual's metabolic phenotype that have detected in enzymes involved in activation and detoxification should play an...
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