Article
A partial model of the erythropoietin receptor complex.
Proteins - 1 Mar 1996
Caravella J A, Lyne P D, Richards W G
Abstract excerpt
A model of the structure of erythropoietin (Epo) is presented based on structural homology to other hemopoietic cytokines. A model of the erythropoietin receptor complex was made based on evidence that this includes a homodimer of the receptor chain with known sequence. Key interactions are noted which explain data from mutation experiments, although at not all residues believed to be important to binding of Epo...
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