Article
Angiotensinogen polymorphism M235T, hypertension, and nephropathy in insulin-dependent diabetes.
Hypertension (Dallas, Tex. : 1979) - 1 May 1996
Doria A, Onuma T, Gearin G, Freire M B, Warram J H, Krolewski A S
Abstract excerpt
The allele 235T (a threonine in place of a methionine at position 235) of angiotensinogen has been found to be associated with a predisposition to essential hypertension. We investigated whether this allele also confers increased susceptibility to nephropathy in patients with insulin-dependent di...
Topics
- Adult
- Alleles
- Angiotensinogen
- Base Sequence
- Diabetes Mellitus, Type 1
- Diabetic Angiopathies
- Diabetic Nephropathies
- Genetic Predisposition to Disease
- Humans
- Hypertension
- Molecular Probes
- Molecular Sequence Data
- Polymorphism, Genetic
