Article
Angiotensinogen polymorphism M235T, hypertension, and nephropathy in insulin-dependent diabetes.
Hypertension (Dallas, Tex. : 1979) - 1 May 1996
Doria A, Onuma T, Gearin G, Freire M B, Warram J H, Krolewski A S
Abstract excerpt
The allele 235T (a threonine in place of a methionine at position 235) of angiotensinogen has been found to be associated with a predisposition to essential hypertension. We investigated whether this allele also confers increased susceptibility to nephropathy in patients with insulin-dependent diabetes mellitus (IDDM). A group of 380 patients who had had IDDM for 15 to 20 years were genotyped at the...
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