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Article

Angiotensinogen gene polymorphisms in IDDM patients with diabetic nephropathy.

Diabetes - 1 Mar 1996

Tarnow L, Cambien F, Rossing P, Nielsen F S, Hansen B V, Ricard S, Poirier O, Parving H H

Abstract excerpt

Genotypic abnormalities of the renin-ANG system have been suggested as a risk factor for the development of diabetic nephropathy. Cleavage of angiotensinogen is the rate-limiting step in the activation of the renin-ANG system. The TT genotype of a polymorphism encoding threonine instead of methionine (M235T) has been associated not only with increased plasma angiotensinogen concentration but also with essential...

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Share to Angiotensinogen
Share to Blood Pressure
Share to Diabetes Mellitus, Type 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Methionine

Share to Polymorphism, Genetic

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Source

Identifiers

PMID: 8593944
DOI: 10.2337/diab.45.3.367

Genes

ANG

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

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Angiotensinogen gene polymorphisms in IDDM patients with diabetic nephropathy.PMID 8593944Read ↗

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A molecular variant of angiotensinogen is associated with diabetic nephropathy in IDDM.Semantic proximity Read ↗

Relationship between angiotensinogen gene M235T variant with diabetic nephropathy in Chinese NIDDM.Semantic proximity Read ↗

Angiotensinogen polymorphism M235T, hypertension, and nephropathy in insulin-dependent diabetes.Semantic proximity Read ↗

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Genetic polymorphisms of the renin-angiotensin-aldosterone system in end-stage renal disease.Semantic proximity Read ↗

Genetic variants of ACE (Insertion/Deletion) and AGT (M268T) genes in patients with diabetes and nephropathy.Semantic proximity Read ↗

Examination of two genetic polymorphisms within the renin-angiotensin system: no evidence for an association with nephropathy in IDDM.Semantic proximity Read ↗

Angiotensinogen gene M235T and T174M polymorphisms in essential hypertension: relation with target organ damage.Semantic proximity Read ↗

Associations between angiotensinogen M235T polymorphisms and the risk of diabetic nephropathy: A meta-analysis.Semantic proximity Read ↗

The effects of angiotensinogen M235T/T174M and angiotensin type 1 receptor a1166c gene polymorphisms on the development of diabetic nephropathy in type 2 diabetes mellitus patients.Semantic proximity Read ↗

Angiotensinogen gene M235T polymorphism is not associated with diabetic nephropathy. The Diabetic Nephropathy Study Group.Semantic proximity Read ↗

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